CHEMBL26379


SMILES N#Cc1ccc2[nH]cc(C3=CCNCC3)c2c1
InChIKey VADZOZAUGGYKFE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 223.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.79 7.79 7.79 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 7.5 7.5 7.5 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pEC50 6.89 6.89 6.89 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.7 7.7 7.7 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 9.1 9.1 9.1 ChEMBL