CHEMBL2435408


SMILES O=C1N(Cc2cccc3[nH]ccc23)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey DCKAOKXRHCMSPN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.26 6.29 6.32 ChEMBL
OX1 OX1R Human Orexin A pKd 6.2 6.2 6.2 ChEMBL
OX2 OX2R Human Orexin A pKi 7.11 7.16 7.2 ChEMBL
OX2 OX2R Human Orexin A pKd 6.89 6.89 6.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database