CHEMBL2333732


SMILES Oc1ccc(N2CCN(Cc3cnn(-c4ccc(Cl)cc4)c3)CC2)cc1
InChIKey HBGSAORKQHKGPY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 368.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Rat Adrenoceptors A pKi 5.19 5.19 5.19 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKi 5.94 5.94 5.94 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.47 7.47 7.47 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.28 6.28 6.28 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.23 5.23 5.23 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 4.91 4.91 4.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database