CHEMBL2206375


SMILES CC(C)N(Cc1cnc[nH]1)c1ccc(Cl)cc1
InChIKey AOHLEOYTKMSKPD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 249.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Human Trace amine A pKi 8.22 8.22 8.22 ChEMBL
TA1 TAAR1 Mouse Trace amine A pKi 8.51 8.51 8.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Rat Trace amine A pEC50 7.6 7.6 7.6 ChEMBL
TA1 TAAR1 Human Trace amine A pEC50 7.64 7.64 7.64 ChEMBL
TA1 TAAR1 Mouse Trace amine A pEC50 7.64 7.64 7.64 ChEMBL