CHEMBL2037432


SMILES OC1(c2ccc(Cl)cc2)CCN(CCCCc2nc3ccccc3s2)CC1
InChIKey CZOXEMUHIJZXSF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 400.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.85 6.85 6.85 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.01 6.01 6.01 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.85 6.85 6.85 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.37 5.37 5.37 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.54 6.54 6.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.7 6.7 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database