CHEMBL194637


SMILES N#Cc1cc(-n2nnc(-c3ccccn3)n2)cc([N+](=O)[O-])c1
InChIKey JYTNLQWXYHIBFN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 293.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.38 7.38 7.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.38 7.38 7.38 ChEMBL