CHEMBL1946124


SMILES O=C1c2ccc(F)cc2CC1CCN1CCCN(c2ccc(Cl)cc2)CC1
InChIKey TUSPVTWVRDALHT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.43 7.43 7.43 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.14 7.14 7.15 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.42 5.42 5.42 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.39 6.61 6.72 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.23 6.23 6.23 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.99 5.99 5.99 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.43 7.43 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database