CHEMBL186133


SMILES c1ccc(-c2nnn(-c3cccc(-c4cccnc4)c3)n2)nc1
InChIKey WXYKFMCIKBZGRS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 300.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.16 7.16 7.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.2 7.2 7.2 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.2 7.2 7.2 ChEMBL