CHEMBL1627323


SMILES O=C(NC/C=C/CN1CCN(c2cccc(Cl)c2Cl)CC1)c1cc2ccccc2[nH]1
InChIKey OKLQUANCQYMFOA-ONEGZZNKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 442.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.03 6.03 6.03 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.19 6.19 6.19 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.71 6.71 6.71 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.36 9.36 9.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 8.15 8.15 8.15 ChEMBL