CHEMBL159022


SMILES COc1ccccc1C(=O)CCCCCN1CCN(c2noc3ccccc23)CC1
InChIKey VRSNKCQWIMHWFX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 407.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 9.05 9.05 9.05 ChEMBL
D3 DRD3 Rat Dopamine A pKi 7.26 7.26 7.26 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.4 8.4 8.4 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.76 6.76 6.76 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.11 7.11 7.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database