CHEMBL140197


SMILES N[C@H](C(=O)O)[C@H]1[C@@H](O)[C@@H]1C(=O)O
InChIKey LGSORWLWDBCUMM-NTAGLIMJSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 3
Molecular weight (Da) 175.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 8.52 8.52 8.52 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.64 7.64 7.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu6 GRM6 Rat Metabotropic glutamate C pEC50 6.83 6.83 6.83 ChEMBL
mGlu8 GRM8 Rat Metabotropic glutamate C pEC50 8.0 8.0 8.0 ChEMBL
mGlu4 GRM4 Rat Metabotropic glutamate C pEC50 5.75 5.75 5.75 ChEMBL
mGlu3 GRM3 Rat Metabotropic glutamate C pEC50 7.96 8.05 8.15 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 8.3 8.35 8.4 ChEMBL