NVP-SAA164


SMILES CN1CCN(CC1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc(c(c1)C(=O)N1CCOCC1)NCC(c1ccccc1)c1ccccc1
InChIKey VODUCDWVPSEMSZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 659.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B1 BKRB1 Human Bradykinin A pKi 7.9 8.0 8.1 Guide to Pharmacology
B1 BKRB1 Rhesus macaque Bradykinin A pKi 8.11 8.11 8.11 ChEMBL
B1 BKRB1 Human Bradykinin A pKi 8.0 8.05 8.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B1 BKRB1 Human Bradykinin A pIC50 7.48 7.48 7.48 ChEMBL