N-((1r,4r)-4-(4-(2-cyclopropoxyphenyl)piperidin-1-yl)cyclohexyl)benzo[d][1,3]dioxole-5-sulfonamide


SMILES CCCCN(CCCC)N=O
InChIKey YGJHZCLPZAZIHH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 158.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Human Adrenoceptors A pKi 6.72 8.08 9.85 PDSP Ki database
α1B ADA1B Human Adrenoceptors A pKi 5.36 6.6 7.51 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.09 7.08 8.72 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.08 7.6 8.77 PDSP Ki database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.0 5.66 6.57 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.0 5.18 5.47 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database