L-817,818


SMILES CC(COC(=O)C(CCCCN)NC(=O)CC1=C(NC2=C1C=CC3=CC=CC=C32)C4=CC5=CC=CC=C5C=C4)N
InChIKey NFVRGDRCCNEGBS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 11
Molecular weight (Da) 536.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST1 SSR1 Human Somatostatin A pKi 8.48 8.48 8.48 PDSP Ki database
SST2 SSR2 Human Somatostatin A pKi 7.28 7.28 7.28 PDSP Ki database
SST3 SSR3 Human Somatostatin A pKi 7.19 7.19 7.19 PDSP Ki database
SST4 SSR4 Human Somatostatin A pKi 7.09 7.09 7.09 PDSP Ki database
SST5 SSR5 Human Somatostatin A pKi 8.89 9.23 9.4 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database