(+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid


SMILES C1CC(C2C1C2C(=O)O)(C(=O)O)N
InChIKey VTAARTQTOOYTES-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 185.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 7.1 7.58 8.05 PDSP Ki database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.07 7.07 7.07 PDSP Ki database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.9 6.9 6.9 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database