CHEMBL73979


SMILES O=C(c1ccc(F)cc1)C1CCN(CCc2ccc(I)cc2)CC1
InChIKey CHWGPAKCKQJKJN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 437.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.75 6.75 6.75 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.84 6.84 6.84 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.44 8.44 8.44 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.52 6.52 6.52 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.13 8.13 8.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database