CHEMBL567198


SMILES CC(=O)N(C)C1CCN(CCC(C)(C(=O)N(C)Cc2ccccc2Cl)c2ccc(Cl)c(Cl)c2)CC1
InChIKey OZJDKUMSRQSURZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 537.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK3 NK3R Guinea pig Tachykinin A pKd 7.53 7.58 7.62 ChEMBL
NK3 NK3R Guinea pig Tachykinin A pKi 7.92 8.01 8.1 ChEMBL
NK3 NK3R Human Tachykinin A pKi 7.98 7.98 7.98 ChEMBL
NK3 NK3R Human Tachykinin A pKd 7.74 7.74 7.74 ChEMBL
NK1 NK1R Human Tachykinin A pKi 7.15 7.15 7.15 ChEMBL
NK2 NK2R Human Tachykinin A pKi 6.02 6.02 6.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database