CHEMBL515170


SMILES CC[C@@H]1O[C@](/C=C/C2CC2)(C(F)(F)F)c2c(ccc(F)c2F)NC1=O
InChIKey MSJCAWWJIHDUAU-OSTNNTLRSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 361.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK2 NK2R Human Tachykinin A pIC50 4.55 4.55 4.55 ChEMBL
α2C ADA2C Human Adrenoceptors A pIC50 4.98 4.98 4.98 ChEMBL
α1D ADA1D Human Adrenoceptors A pIC50 4.86 4.86 4.86 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 4.82 4.82 4.82 ChEMBL
PTH1 PTH1R Human Parathyroid hormone B1 pIC50 4.17 5.14 6.0 ChEMBL