GW803430
| SMILES | COc1cc(ccc1OCCN1CCCC1)n1cnc2c(c1=O)sc(c2)c1ccc(cc1)Cl |
| InChIKey | MWULMTACIBZPGN-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 7 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 7 |
| Molecular weight (Da) | 481.1 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| MCH1 | MCHR1 | Rat | Melanin-concentrating hormone | A | pKi | 9.47 | 9.47 | 9.47 | ChEMBL |
| H3 | HRH3 | Human | Histamine | A | pKi | 6.68 | 6.68 | 6.68 | ChEMBL |
| MCH1 | MCHR1 | Human | Melanin-concentrating hormone | A | pKi | 8.55 | 8.55 | 8.55 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| MCH1 | MCHR1 | Human | Melanin-concentrating hormone | A | pIC50 | 9.3 | 9.3 | 9.3 | Guide to Pharmacology |
| MCH1 | MCHR1 | Human | Melanin-concentrating hormone | A | pIC50 | 7.05 | 8.36 | 9.3 | ChEMBL |