CHEMBL1277837


SMILES CC(C)n1nc(S(=O)(=O)c2cccc3ccccc23)c2cc(N3CCNCC3)ccc21
InChIKey YKEFFXDXDCCGLC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 434.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.02 7.02 7.02 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.54 8.54 8.54 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.69 5.69 5.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 8.54 8.54 8.54 ChEMBL