CHEMBL4872800


SMILES O=C1c2ccc(Cl)cc2CC1CCN1CCN(c2ccccn2)CC1
InChIKey UAVSIHCMQXGAIV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 355.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.84 7.84 7.85 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.19 7.19 7.19 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.7 5.7 5.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.95 6.95 6.95 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database