CHEMBL4872713


SMILES O=C1c2ccccc2S(=O)(=O)N1CCCCCN1CCN(c2ccccc2)CC1
InChIKey MDLOPRPXCUEGCT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 413.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.83 6.83 6.83 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.74 5.74 5.74 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.78 6.78 6.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database