CHEMBL4859295


SMILES COc1cc2c(cc1Cl)nc(OC)n2CCNC(C)=O
InChIKey BVSLRGAPRGQWNC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 297.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT2 MTR1B Human Melatonin A pKi 9.1 9.1 9.1 ChEMBL
MT1 MTR1A Human Melatonin A pKi 8.68 8.68 8.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT2 MTR1B Human Melatonin A pEC50 9.07 9.07 9.07 ChEMBL
MT1 MTR1A Human Melatonin A pEC50 9.6 9.9 10.2 ChEMBL