CHEMBL4848305


SMILES Clc1cccc(-c2n[nH]cc2N2CCNCC2)c1
InChIKey ZRPDKOIUHULZCY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 262.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.63 5.63 5.63 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.73 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.21 7.21 7.21 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.12 7.12 7.12 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.08 6.08 6.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.04 6.04 6.04 ChEMBL