CHEMBL4845741


SMILES Nc1ccc(CCCCN2CCN(c3ccccn3)CC2)cc1
InChIKey PGTMRNBGCGSJFJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 310.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.56 6.61 6.65 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.73 5.73 5.73 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.87 7.88 7.89 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.41 6.41 6.41 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.17 6.17 6.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database