CHEMBL4803084


SMILES N[C@@]1(C(=O)O)[C@H](CSCc2ccc(Cl)c(Cl)c2)[C@@H](O)[C@@H]2[C@H]1[C@H]2C(=O)O
InChIKey OSPUMEGCPJZZKB-PMVMBDLWSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 6
Molecular weight (Da) 405.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.79 7.79 7.79 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.69 7.69 7.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 7.21 7.21 7.21 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 7.31 7.31 7.31 ChEMBL