CHEMBL4587772


SMILES CCOc1ccccc1N1CCN(CCCCCCN2C(=O)c3cccc4cccc2c34)CC1
InChIKey FJGNCKIPBKWGFB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 457.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.08 7.08 7.08 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.96 7.96 7.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database