CHEMBL1258037


SMILES Cc1ccc(C)c(N2CCN(CCCC(=O)c3ccc(F)cc3)CC2)c1
InChIKey YJHBORBWSSPLGN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 354.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.68 6.68 6.68 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.77 7.77 7.77 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.12 7.12 7.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.8 7.84 7.89 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.07 6.07 6.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database