CHEMBL4537701


SMILES CCC(=O)Nc1nc(C)c(-c2cn(S(=O)(=O)c3ccccc3)c3ccc(F)cc23)[nH]1
InChIKey TUEMKIYKYXEZDB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 426.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.07 5.07 5.07 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.97 6.97 6.97 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.1 5.1 5.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database