CHEMBL4519004


SMILES COc1ccc2c(c1)c(-c1[nH]c(NCCc3ccccc3)nc1C)cn2S(=O)(=O)c1ccccc1
InChIKey JJMRPVGTDRDQOU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 486.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.08 7.08 7.08 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.67 5.67 5.67 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database