CHEMBL440120


SMILES N#CC(C#N)=Cc1[nH]ccc1CN1CCN(c2ccccc2)CC1
InChIKey JXPFVJLJUKGXQP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 317.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.66 4.66 4.66 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.8 6.8 6.8 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.16 5.16 5.16 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.89 5.14 5.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database