CHEMBL4294799


SMILES O=C1CCc2cc(C(O)CCCN3CCC(c4noc5cc(F)ccc45)CC3)cc3c2N1CC3
InChIKey XAWSBCLNNJQTCA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 463.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.34 7.34 7.34 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.13 6.13 6.13 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 6.47 6.47 6.47 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.87 7.87 7.87 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.2 8.2 8.2 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.65 7.65 7.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database