CHEMBL4290311


SMILES O=C1CCc2cc(C(O)CCCCN3CCC(c4noc5cc(F)ccc45)CC3)cc3c2N1CC3
InChIKey HRYKMSOBBFZAAT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 477.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 6.93 6.93 6.93 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.47 7.47 7.47 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 7.36 7.36 7.36 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.08 8.08 8.08 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.53 7.53 7.53 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database