CHEMBL4283548


SMILES O=C1CCc2cc(CCCCN3CCC(c4noc5cc(F)ccc45)CC3)cc3c2N1CC3
InChIKey UIXQJBAAWGMZKH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 447.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.26 7.26 7.26 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 6.15 6.15 6.15 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.93 7.93 7.93 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database