CHEMBL4214208


SMILES O=C1Nc2ccccc2C12CCN(CCN1CCC(c3ccc(Cl)cc3)CC1)C2
InChIKey HKEJCVZPKVGQNA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 409.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.55 6.55 6.55 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.34 5.34 5.34 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.83 4.83 4.83 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database