CHEMBL4202947


SMILES O=C1Nc2ccccc2C12CCN(CCN1CC=C(c3ccc(F)cc3)CC1)C2
InChIKey DIULDFKKODRGEB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.37 7.37 7.37 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.2 5.2 5.2 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.4 5.4 5.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.12 7.12 7.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database