METHIOTHEPINE


SMILES CSc1ccc2c(c1)C(CCN)=CC2
InChIKey RTASPUXNIKGFBD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 205.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations 5-HT1A 5-HT1B 5-HT2C 5-HT6 5-HT7

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 8.7 8.7 8.7 ChEMBL
D2 DRD2 Rat Dopamine A pKi 9.7 9.7 9.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 8.66 8.66 8.66 ChEMBL