CHEMBL4111384


SMILES Cc1cccc(C(=O)N[C@@]23CCC[C@@](NC(=O)c4ccccn4)(CC2)C3)n1
InChIKey OCVKYJFCWLTEPM-RTWAWAEBSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 364.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pKi 7.41 7.41 7.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 9.49 9.49 9.49 ChEMBL