CHEMBL4080398


SMILES O=S(=O)(c1cccc2ncccc12)N1CCC(CCN2CCN(c3ccc(Cl)cc3)CC2)CC1
InChIKey AELYPESLFOQFTR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 498.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.43 7.43 7.43 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.99 5.99 5.99 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.13 6.13 6.13 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.82 6.82 6.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.85 6.85 6.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database