CHEMBL397121


SMILES Cc1cccc(NC(=O)c2cc(-c3cc(F)cc(F)c3)ccn2)n1
InChIKey CVBWBHLJBLFSFF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 325.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.37 7.37 7.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.01 7.01 7.01 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 6.8 6.8 6.8 ChEMBL