CHEMBL3884325


SMILES O=c1ccc(OCCCN2CCC(c3noc4cc(F)ccc34)CC2)nn1-c1cc(F)ccc1F
InChIKey YGAQJVYCLILFBJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 484.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 8.04 8.04 8.04 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 6.94 6.94 6.94 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.21 8.21 8.21 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.42 8.42 8.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database