CHEMBL3818200


SMILES N#Cc1ccc(C(=O)CCCN2CCc3ccccc3C2)cc1
InChIKey JPXQQLVVAAHNSC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 304.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.46 6.46 6.46 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.12 6.23 6.35 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.12 6.12 6.12 ChEMBL
H1 HRH1 Human Histamine A pKi 6.75 6.78 6.8 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.82 6.82 6.82 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.53 6.53 6.53 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.47 6.47 6.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.84 5.84 5.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database