CHEMBL119455


SMILES CN1CCc2cccc3c2[C@H]1Cc1cccc(O)c1-3
InChIKey PCGXWSCASZVBJT-CQSZACIVSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 251.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 7.58 7.66 7.69 ChEMBL
D1 DRD1 Human Dopamine A pKi 7.21 7.21 7.21 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.97 6.97 6.97 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.02 8.02 8.02 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.31 7.31 7.31 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.68 7.09 7.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 6.96 6.96 6.97 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 7.24 7.24 7.24 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pEC50 5.28 5.28 5.28 ChEMBL