CHEMBL3672911


SMILES Cn1cnc2c1CCN(C(=O)c1cc3ncc(Br)cn3n1)CC2
InChIKey HTTCOCDHRFMKBF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 374.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 6.16 6.16 6.16 ChEMBL