CHEMBL3669546


SMILES Cc1ccc2oc(N3CCC4(CCCC(=O)N4Cc4cccc5[nH]ccc45)CC3)nc2c1
InChIKey KCMMYXVXOINAMH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 428.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.8 5.8 5.8 ChEMBL
OX1 OX1R Human Orexin A pKi 6.18 6.18 6.18 ChEMBL
OX2 OX2R Human Orexin A pKd 6.42 6.42 6.42 ChEMBL
OX2 OX2R Human Orexin A pKi 7.09 7.09 7.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database