CHEMBL3669493


SMILES O=C1N(Cc2cccc3nonc23)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey PJWQHKSCRITWEY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 428.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.63 5.63 5.63 ChEMBL
OX1 OX1R Human Orexin A pKi 5.94 5.94 5.94 ChEMBL
OX2 OX2R Human Orexin A pKd 5.83 5.83 5.83 ChEMBL
OX2 OX2R Human Orexin A pKi 7.01 7.01 7.01 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database