CHEMBL3663411


SMILES COc1cccc(OC)c1C(=O)N1C2CCC1C(COc1ccc(F)cn1)C2
InChIKey MFJLFVLFCUKOQE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 6.52 6.52 6.52 ChEMBL
OX2 OX2R Human Orexin A pKi 6.81 6.81 6.81 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database