CHEMBL3659243


SMILES CCOc1ccc2cccnc2c1C(=O)N1C2CCC1C(COc1ccccn1)C2
InChIKey GMTZECCVYNQQFY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 403.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 7.75 7.75 7.75 ChEMBL
OX1 OX1R Human Orexin A pKi 8.15 8.15 8.15 ChEMBL
OX2 OX2R Human Orexin A pKi 6.66 6.66 6.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database