CHEMBL3648365


SMILES CCc1nc2ccc3c(c2o1)C(CCNC(C)=O)CC3
InChIKey FIPHYUVXAUQDEU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 272.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT2 MTR1B Human Melatonin A pKi 9.8 9.8 9.8 ChEMBL
MT1 MTR1A Human Melatonin A pKi 9.66 9.66 9.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT2 MTR1B Human Melatonin A pIC50 9.39 9.39 9.39 ChEMBL
MT1 MTR1A Human Melatonin A pIC50 9.44 9.44 9.44 ChEMBL