CHEMBL362487


SMILES O=S(=O)(c1ccccc1Cl)n1cc(C2=CCNCC2)c2ccccc21
InChIKey WJCGMHIIDQGXLP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 372.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 9.4 9.4 9.4 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.22 6.22 6.22 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.2 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 8.06 8.06 8.06 ChEMBL